Breast Cancer Research

(ISSN: 1465-5411,1465-542X)

Articles Available on Medscape

 
 

Table of Contents

From Breast Cancer Research

2018 - 20 (1)

  • Long-term exposure to road traffic noise and incidence of breast cancer: a cohort study. 
  • Maternal breast cancer risk in relation to birthweight and gestation of her offspring. 
  • Breast cancer survival predicted by TP53 mutation status differs markedly depending on treatment. 
  • Membrane associated collagen XIII promotes cancer metastasis and enhances anoikis resistance. 
  • BHLHE40 confers a pro-survival and pro-metastatic phenotype to breast cancer cells by modulating HBEGF secretion. 
  • Foxf2 plays a dual role during transforming growth factor beta-induced epithelial to mesenchymal transition by promoting apoptosis yet enabling cell junction dissolution and migration. 
  • Efficient and tumor-specific knockdown of MTDH gene attenuates paclitaxel resistance of breast cancer cells both in vivo and in vitro. 
  • Breast cancer risk factors, survival and recurrence, and tumor molecular subtype: analysis of 3012 women from an indigenous Asian population. 
  • Nogo-B receptor increases the resistance to tamoxifen in estrogen receptor-positive breast cancer cells. 
  • Mucosal associated invariant T cells from human breast ducts mediate a Th17-skewed response to bacterially exposed breast carcinoma cells. 
  • A phase Ib study of pictilisib (GDC-0941) in combination with paclitaxel, with and without bevacizumab or trastuzumab, and with letrozole in advanced breast cancer. 
  • Correction to: Intracellular hypoxia measured by F-18 fluoromisonidazole positron emission tomography has prognostic impact in patients with estrogen-receptor positive breast (BRCR-D17-00693). 
  • Evaluation of anti-PD-1-based therapy against triple-negative breast cancer patient-derived xenograft tumors engrafted in humanized mouse models. 
  • Obesity promotes the expansion of metastasis-initiating cells in breast cancer. 
  • European Network of Breast Development and Cancer turned 10 years: a growing family of mammary gland researchers. 
  • NOTCH3 expression is linked to breast cancer seeding and distant metastasis. 
  • Key regulators of lipid metabolism drive endocrine resistance in invasive lobular breast cancer. 
  • Novel 18-gene signature for predicting relapse in ER-positive, HER2-negative breast cancer. 
  • Magnetic resonance imaging and molecular features associated with tumor-infiltrating lymphocytes in breast cancer. 
  • Epigenomics of mammary gland development. 
  • Correction to: Heregulin β1 drives gefitinib-resistant growth and invasion in tamoxifen-resistant MCF-7 breast cancer cells. 
  • Paternal malnutrition programs breast cancer risk and tumor metabolism in offspring. 
  • TNFAIP3 is required for FGFR1 activation-promoted proliferation and tumorigenesis of premalignant DCIS.COM human mammary epithelial cells. 
  • Breast fibroadenomas are not associated with increased breast cancer risk in an African American contemporary cohort of women with benign breast disease. 
  • Polyfunctional anti-human epidermal growth factor receptor 3 (anti-HER3) antibodies induced by HER3 vaccines have multiple mechanisms of antitumor activity against therapy resistant and triple negative breast cancers. 
  • High mammographic density in women is associated with protumor inflammation. 
  • Long-term exposure to insulin and volumetric mammographic density: observational and genetic associations in the Karma study. 
  • Thyroid hormones and breast cancer association according to menopausal status and body mass index. 
  • Clonal relatedness in tumour pairs of breast cancer patients. 
  • Volumetric breast density and risk of advanced cancers after a negative screening episode: a cohort study. 
  • Correction to: Expression of quiescin sulfhydryl oxidase 1 is associated with a highly invasive phenotype and correlates with a poor prognosis in luminal B breast cancer. 
  • Breast cancer patients suggestive of Li-Fraumeni syndrome: mutational spectrum, candidate genes, and unexplained heredity. 
  • Targeted next-generation sequencing identifies clinically relevant somatic mutations in a large cohort of inflammatory breast cancer. 
  • Can novel technologies improve breast conserving surgery? 
  • Nitric oxide deficiency and endothelial-mesenchymal transition of pulmonary endothelium in the progression of 4T1 metastatic breast cancer in mice. 
  • The added value of mammography in different age-groups of women with and without BRCA mutation screened with breast MRI. 
  • Effect of exercise and/or reduced calorie dietary interventions on breast cancer-related endogenous sex hormones in healthy postmenopausal women. 
  • Tricho-rhino-phalangeal syndrome 1 protein functions as a scaffold required for ubiquitin-specific protease 4-directed histone deacetylase 2 de-ubiquitination and tumor growth. 
  • A phase II clinical trial of the Aurora and angiogenic kinase inhibitor ENMD-2076 for previously treated, advanced, or metastatic triple-negative breast cancer. 
  • Correction to: Association of invasion-promoting tenascin-C additional domains with breast cancers in young women. 
  • Intracellular hypoxia measured by 18F-fluoromisonidazole positron emission tomography has prognostic impact in patients with estrogen receptor-positive breast cancer. 
  • The Prosigna gene expression assay and responsiveness to adjuvant cyclophosphamide-based chemotherapy in premenopausal high-risk patients with breast cancer. 
  • Retraction Note: Nuclear factor of activated T cells 5 maintained by Hotair suppression of miR-568 upregulates S100 calcium binding protein A4 to promote breast cancer metastasis. 
  • Pyruvate carboxylase supports the pulmonary tropism of metastatic breast cancer. 
  • ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis. 
  • Estrogen promotes estrogen receptor negative BRCA1-deficient tumor initiation and progression. 
  • The association of genomic lesions and PD-1/PD-L1 expression in resected triple-negative breast cancers. 
  • Intrinsic molecular subtypes of breast cancers categorized as HER2-positive using an alternative chromosome 17 probe assay. 
  • Intra-operative spectroscopic assessment of surgical margins during breast conserving surgery. 
  • Correction to: The mTOR inhibitor rapamycin down-regulates the expression of the ubiquitin ligase subunit Skp2 in breast cancer cells. 
  • Evaluation of α-tubulin, detyrosinated α-tubulin, and vimentin in CTCs: identification of the interaction between CTCs and blood cells through cytoskeletal elements. 
  • Syndecan-1 induction in lung microenvironment supports the establishment of breast tumor metastases. 
  • Identification and validation of single-sample breast cancer radiosensitivity gene expression predictors. 
  • Glucocorticoids promote transition of ductal carcinoma in situ to invasive ductal carcinoma by inducing myoepithelial cell apoptosis. 
  • Correction to: Identification of the functional role of peroxiredoxin 6 in the progression of breast cancer. 
  • Correction to: Nongenomic oestrogen signalling in oestrogen receptor negative breast cancer cells: a role for the angiotensin II receptor AT1. 
  • Can diffusion-weighted imaging predict tumor grade and expression of Ki-67 in breast cancer? A multicenter analysis. 
  • Expression of ID4 protein in breast cancer cells induces reprogramming of tumour-associated macrophages. 
  • SNAI2 upregulation is associated with an aggressive phenotype in fulvestrant-resistant breast cancer cells and is an indicator of poor response to endocrine therapy in estrogen receptor-positive metastatic breast cancer. 
  • Correction to: Buthionine sulfoximine sensitizes antihormone-resistant human breast cancer cells to estrogen-induced apoptosis. 
  • Identifying an early treatment window for predicting breast cancer response to neoadjuvant chemotherapy using immunohistopathology and hemoglobin parameters. 
  • NDRG1 regulates neutral lipid metabolism in breast cancer cells. 
  • Simultaneous blockade of IL-6 and CCL5 signaling for synergistic inhibition of triple-negative breast cancer growth and metastasis. 
  • Metformin inhibits stromal aromatase expression and tumor progression in a rodent model of postmenopausal breast cancer. 
  • Generation of HER2-specific antibody immunity during trastuzumab adjuvant therapy associates with reduced relapse in resected HER2 breast cancer. 
  • Amide chemical exchange saturation transfer at 7 T: a possible biomarker for detecting early response to neoadjuvant chemotherapy in breast cancer patients. 
  • OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung. 
  • Exploring the prediction performance for breast cancer risk based on volumetric mammographic density at different thresholds. 
  • Longitudinal enumeration and cluster evaluation of circulating tumor cells improve prognostication for patients with newly diagnosed metastatic breast cancer in a prospective observational trial. 
  • Targeting tumour re-wiring by triple blockade of mTORC1, epidermal growth factor, and oestrogen receptor signalling pathways in endocrine-resistant breast cancer. 
  • Correction to: Identification of novel human RANK isoforms generated through alternative splicing. Implications in breast cancer cell survival and migration. 
  • A survey of microRNA single nucleotide polymorphisms identifies novel breast cancer susceptibility loci in a case-control, population-based study of African-American women. 
  • Quantitative background parenchymal uptake on molecular breast imaging and breast cancer risk: a case-control study. 
  • Proteolytic single hinge cleavage of pertuzumab impairs its Fc effector function and antitumor activity in vitro and in vivo. 
  • Hyperprolactinemia-inducing antipsychotics increase breast cancer risk by activating JAK-STAT5 in precancerous lesions. 
  • Contributions of the RhoA guanine nucleotide exchange factor Net1 to polyoma middle T antigen-mediated mammary gland tumorigenesis and metastasis. 
  • Circulating ESR1 mutations at the end of aromatase inhibitor adjuvant treatment and after relapse in breast cancer patients. 
  • Real-world evidence analysis of palbociclib prescribing patterns for patients with advanced/metastatic breast cancer treated in community oncology practice in the USA one year post approval. 
  • Assessing brain volume changes in older women with breast cancer receiving adjuvant chemotherapy: a brain magnetic resonance imaging pilot study. 
  • The combined effect of mammographic texture and density on breast cancer risk: a cohort study. 
  • Dependence receptor UNC5A restricts luminal to basal breast cancer plasticity and metastasis. 
  • IMP1 regulates UCA1-mediated cell invasion through facilitating UCA1 decay and decreasing the sponge effect of UCA1 for miR-122-5p. 
  • Comparison of methods to assess onset of breast development in the LEGACY Girls Study: methodological considerations for studies of breast cancer. 
  • MRI-based response patterns during neoadjuvant chemotherapy can predict pathological (complete) response in patients with breast cancer. 
  • Mitochondrial DNA copy number variation, leukocyte telomere length, and breast cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. 
  • Morphology and genomic hallmarks of breast tumours developed by ATM deleterious variant carriers. 
  • Common genetic variation and novel loci associated with volumetric mammographic density. 
  • Isocitrate dehydrogenase 1-snail axis dysfunction significantly correlates with breast cancer prognosis and regulates cell invasion ability. 
  • Effect of neoadjuvant chemotherapy regimen on relapse-free survival among patients with breast cancer achieving a pathologic complete response: an early step in the de-escalation of neoadjuvant chemotherapy. 
  • Practice patterns and outcomes for patients with node-negative hormone receptor-positive breast cancer and intermediate 21-gene Recurrence Scores. 
  • A novel neuregulin - jagged1 paracrine loop in breast cancer transendothelial migration. 
  • Functional genomics identifies specific vulnerabilities in PTEN-deficient breast cancer. 
  • The amino acid transporter SLC7A5 confers a poor prognosis in the highly proliferative breast cancer subtypes and is a key therapeutic target in luminal B tumours. 
  • Murine breast cancer feed arteries are thin-walled with reduced α1A-adrenoceptor expression and attenuated sympathetic vasocontraction. 
  • Increased circulating resistin levels in early-onset breast cancer patients of normal body mass index correlate with lymph node negative involvement and longer disease free survival: a multi-center POSH cohort serum proteomics study. 
  • Assessment of performance of the Gail model for predicting breast cancer risk: a systematic review and meta-analysis with trial sequential analysis. 
  • The origins of breast cancer associated with mammographic density: a testable biological hypothesis. 
  • The hypoxic tumor microenvironment in vivo selects the cancer stem cell fate of breast cancer cells. 
  • Prognostic impact of CD4-positive T cell subsets in early breast cancer: a study based on the FinHer trial patient population. 
  • Affinity proteomic profiling of plasma for proteins associated to area-based mammographic breast density. 
  • Not all false positive diagnoses are equal: On the prognostic implications of false-positive diagnoses made in breast MRI versus in mammography / digital tomosynthesis screening. 
  • Frequency of breast cancer subtypes among African American women in the AMBER consortium. 
  • The significance of tumour microarchitectural features in breast cancer prognosis: a digital image analysis. 
  • A comparison of five methods of measuring mammographic density: a case-control study. 
  • Integrin-uPAR signaling leads to FRA-1 phosphorylation and enhanced breast cancer invasion. 
  • BRIP1 loss-of-function mutations confer high risk for familial ovarian cancer, but not familial breast cancer. 
  • Inherited factors contribute to an inverse association between preeclampsia and breast cancer. 
  • Body mass index at age 18 years and recent body mass index in relation to risk of breast cancer overall and ER/PR/HER2-defined subtypes in white women and African-American women: a pooled analysis. 
  • Evaluating the breast cancer predisposition role of rare variants in genes associated with low-penetrance breast cancer risk SNPs. 
  • SNPs related to vitamin D and breast cancer risk: a case-control study. 
  • Identifying biomarkers of breast cancer micrometastatic disease in bone marrow using a patient-derived xenograft mouse model. 
 
 

Journal Information

Mission Statement: Breast Cancer Research is a multidisciplinary journal edited by Bruce Ponder, Lewis Chodosh, Stephen Johnston and an international editorial board.

 
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