Genomics News

 
 
  • Herpesvirus May Drive Development, Progression of Alzheimer's In potentially game-changing research, a novel study of postmortem brain samples suggests human herpesvirus may be implicated in the neuropathology of Alzheimer's disease.
  • Common Psychiatric Disorders Share Genetic Underpinnings A massive new study finds a high degree of genetic overlap between psychiatric disorders that current clinical diagnostic categories do not accurately reflect.
  • Sulfonylureas Work Long-Term in Permanent Neonatal Diabetes In contrast to type 2 diabetes, sulfonylureas appear not to lose efficacy over time or cause hypoglycemia in patients with a rare form of diabetes, neonatal arising from KCNJ11 mutations.
  • Doctors Have Cost Concerns About Genetic Tests for Disease Risk While many primary care providers believe genetic tests to assess risk for common chronic diseases might prove useful in treating patients, a recent study also suggests they're worried that steep out-of-pocket costs may limit who can be tested.
  • Theranos Founder Holmes, President Balwani Indicted Theranos Inc founder Elizabeth Holmes and the blood testing company’s former president, Ramesh 'Sunny' Balwani, have been indicted by a federal grand jury in California on charges of wire fraud, the US Justice Department said on Friday.
  • Hong Kong Market Could Open Cash Flood Gates for U.S. Biotechs When U.S. biotech startup Sorrento Therapeutics named ex-Lehman Brothers executive Jiong Shao as its new finance chief about two months ago, it was widely seen as a move driven by his background in raising capital for Alibaba and Tencent.
  • Late-Onset Crohn's Disease Resembles Ulcerative Colitis Crohn's disease (CD) diagnosed at age 55 years or later resembles ulcerative colitis (UC) and should be considered a distinct subgroup of inflammatory bowel disease (IBD), researchers report.
  • EANFourth EAN Meeting Tackles Theme of Neurogenetics New insights into genetic influences on brain disorders are emerging every day, says the president of the European Academy of Neurology.
  • Active Women in Their 70s Beat Genetic Propensity to Obesity 'Our findings point to the importance of promoting and maintaining healthy behaviors particularly in older adults to maximize quality of life,' say the researchers.
  • Gene Editing Tool May Raise Cancer Risk in Cells, Scientists Warn A gene-editing technology that is being explored by scientists worldwide as a way of removing and replacing gene defects might inadvertently increase cancer risk in cells, scientists warned on Monday.
  • Scientists Map Genetic Codes Of 3,000 Dangerous Bacteria Scientists seeking new ways to fight drug-resistant superbugs have mapped the genomes of more than 3,000 bacteria, including samples of a bug taken from Alexander Fleming's nose and a dysentery-causing strain from a World War One soldier.
  • Variability in Gene-sequencing Panels Could Mean Missed Early-life Epilepsy Diagnoses Variability among next-generation sequencing (NGS) panels for early-life epilepsies could cause some confirmed epilepsy genes to be missed, researchers report.
  • ASCO 2018Detecting Lung Cancer From Simple Blood Draw Two years ago it was a 'pipe dream', but a new study show that a simple blood test for circulating tumor DNA can detect lung cancer; the dream inches ever closer to becoming a reality.
  • ASCO 2018Test All Patients With MSI Tumors for Lynch Syndrome Tumors that have high microsatellite instability are more likely to be linked to Lynch syndrome; this includes tumors that have not been previously associated with the syndrome.
  • With Prostate Cancer, Race Is Not Entirely Black and White When black and white men receive the same treatment for prostate cancer, they have the same outcomes, according to two new studies. Why might this not hold true outside of clinical trials?
  • Alert CHMP Advises Against Approval for Eteplirsen in DMD The EMA's Committee for Medicinal Products for Human Use recommends against approval of eteplirsen for Duchenne muscular dystrophy but extends approval of ataluren to younger patients with the disease.
  • Scientists Hunt Down Genes Behind Humankind's Big Brain Scientists have pinpointed three genes that may have played a pivotal role in an important milestone in human evolution: the striking increase in brain size that facilitated cognitive advances that helped define what it means to be human.
  • Genesis of Schizophrenia May Lie in the Placenta In what is being described as a groundbreaking study, researchers found that schizophrenia risk genes are predominantly expressed in the placenta.
  • Algorithm Allows Automated Blood Typing A new algorithm based on whole-genome sequencing (bloodTyper) allows automated typing of red blood cell (RBC) and platelet antigens, researchers report.
  • BRAF Mutations Tied to Post-surgery Prognosis in Colorectal Liver Cancer The V600E BRAF mutation is associated with poorer prognosis and increased risk of recurrence in patients who have undergone resection of colorectal liver metastases (CRLM), according to a large cohort study.
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